1．教育状况

2010.09-2014.06：东北农业大学网投最安全信誉最好网站，动物科学，学士

2014.09-2017.06：东北农业大学网投最安全信誉最好网站，动物营养与饲料科学，硕士，导师：单安山

2017.09-2021.06：东北农业大学网投最安全信誉最好网站，动物营养与饲料科学，博士，导师：单安山

2．工作经历

2021.10-至今：东北农业大学网投最安全信誉最好网站，副教授，硕士研究生导师

2022.04-至今：东北农业大学生命科学学院，博士后，合作导师：向文胜

3.主要成果

代表性论文（第一作者）：

[1]Changxuan Shao#, Qiao Jian#, Bowen Li, Yongjie Zhu, Weikang Yu, Zhongyu Li, Anshan Shan*. Ultrashort All-Hydrocarbon Stapled α-Helix Amphiphile as a Potent and Stable Antimicrobial Compound. Journal of Medicinal Chemistry, 2023, 66, 11414-11427.SCI,IF7.3

[2]Changxuan Shao#, Yongjie Zhu#, Qiao Jian, Zhenheng Lai, Peng Tan, Guoyu Li, Anshan Shan*. Cross-Strand Interaction, Central Bending, and Sequence Pattern Act as Biomodulators of Simplified β-Hairpin Antimicrobial Amphiphiles. Small, 2021, 17(7), 2003899. SCI,IF13.3

[3]Chensi Wang#,Changxuan Shao#, Yuxin Fang, Jiajun Wang, Na Dong*, Anshan Shan*. Binding Loop of Sunflower Trypsin Inhibitor 1 Serves as a Design Motif for Proteolysis-Resistant Antimicrobial Peptides. Acta Biomaterialia, 2021, 124: 254-269. SCI,IF9.7

[4]Yongjie Zhu#,Changxuan Shao#, Guoyu Li, Zhenheng Lai, Peng Tan, Qiao Jian, Baojing Cheng, Anshan Shan*. Rational Avoidance of Protease Cleavage Sites and Symmetrical End-Tagging Significantly Enhances the Stability and Therapeutic Potential of Antimicrobial Peptides. Journal of Medicinal Chemistry, 2020, 63(17), 9421-9435. SCI,IF7.3

[5]Changxuan Shao#,Weizhong Li#, Peng Tan, Anshan Shan*, Xiujing Dou, Deying Ma*, Chunyu Liu. Symmetrical Modification of Minimized Dermaseptins to Extend the Spectrum of Antimicrobials with Endotoxin Neutralization Potency. International Journal of Molecular Sciences, 2019, 20 (6), 1417. SCI,IF5.6

[6]Changxuan Shao#, Yongjie Zhu#, Zhenheng Lai, Peng Tan, Anshan Shan*. Antimicrobial Peptides with Protease Stability: Progress and Perspective. Future Medicinal Chemistry, 2019, 11(16), 2047-2050. SCI,IF4.2

[7]Changxuan Shao#, Weizhong Li#, Zhenheng Lai, Muhammad Usman Akhtar, Na Dong, Anshan Shan*, Deying Ma*. Effect of Terminal Arrangement of Tryptophan on Biological Activity of Symmetric α-helix-Forming Peptides. Chemical Biology & Drug Design, 2019, 94, 2051-2063. SCI,IF3.0

[8]Changxuan Shao, Haotian Tian, Tianyu Wang, Zhihua Wang, Shuli Chou, Anshan Shan*, Baojing Cheng. Central β-turn Increases the Cell Selectivity of Imperfectly Amphipathic α-helical Peptides. Acta Biomaterialia, 2018, 69, 243-255. SCI,IF9.7

[9]邵长轩，赵光辉，朱永杰，于伟康，关红蕊，单安山*.人源Cathelicidins家族抗菌肽LL-37生物学功能和分子修饰研发进展，东北农业大学学报，2023，54(7):80-90.

[10]邵长轩，党安凯，战昭含，来振衡，朱永杰，单安山*.β-折叠抗菌肽的研发及应用策略，畜牧兽医学报，2022，53(08)：2490-2501.

专利：

[1]邵长轩；邓浩然；于伟康；康靖童；单安山。ZL202211522701.2

[2]邵长轩；关红蕊；康靖童；单安山。ZL202211245805.3

[3]邵长轩；关红蕊；王袁梦雪；康靖童；单安山。ZL202211245843.9

[4]邵长轩；王袁梦雪；朱永杰；康靖童；单安山。ZL202211249460.9

[5]单安山；邵长轩；李国雨。ZL202010234840.X

[6]单安山；邵长轩；来振衡。ZL202010234599.0

[7]单安山；邵长轩；菅俏。ZL202010234621.1

[8]单安山；邵长轩；谭鹏。ZL202010234588.2

[9]单安山；邵长轩；朱永杰。ZL202010234622.6

[10]单安山；邵长轩。ZL201710300205.5

在研课题

[1]中国博士后科学基金第72批面上资助（二等），2023.01 ~ 2024.12，主持

[2]黑龙江省博士后面上资助（一等），2023.01 ~ 2024.12，主持

[3]新时代龙江优秀硕士、博士学位论文资助一般项目，2022.10 ~ 2025.10，主持

[4]黑龙江省自然科学基金优秀青年项目，2022.07 ~ 2025.07，主持

[5]东北农业大学高层次人才引进项目，2021.10 ~ 2024.10，主持

[6]国家自然科学基金联合基金项目，2022.01 ~ 2025.12，参与5/10

[7]国家自然科学基金重点项目，2021.01 ~ 2025.12，参与6/9